| S Gents s-gents.com | 1 | News |
| Saily saily.com | 7 | News |
| Salt and Stone saltandstone.com | 6 | Society & Culture |
| Salviospizza salviospizza.com | 1 | Sports |
| Sam Edelman samedelman.com | 4 | Society & Culture |
| Samuel Adams samueladams.com | 2 | Sports |
| Santabarbarachocolate santabarbarachocolate.com | 1 | Health & Fitness |
| SAVA savanutrition.com | 1 | Health & Fitness |
| Savage Arms savagearms.com | 1 | Leisure |
| Savvy Ladies Free Financial Helpline savvyladies.org | 1 | Health & Fitness |
| Sawyer Products sawyer.com | 1 | Arts |
| Schedule35 schedule35.co | 2 | Comedy |
| Scrunch scrunch.com | 2 | Business |
| Scuf scuf.co | 1 | Technology |
| SEAT GEEK seatgeek.com | 4 | News |
| Seed seed.com | 8 | Health & Fitness |
| Seedlang seedlang.com | 1 | Education |
| Select Quote selectquote.com | 8 | News |
| Sentry sentry.io | 4 | Technology |
| Sentry H2O sentryh2o.com | 1 | Society & Culture |
| Sephora sephora.com | 1 | Health & Fitness |
| Sequencing sequencing.com | 6 | True Crime |
| SerpAPI serpapi.com | 3 | Technology |
| Seven Weeks Coffee sevenweekscoffee.com | 1 | Society & Culture |
| Shady Rays shadyrays.com | 15 | Sports |
| Shakeology shakeology.com | 1 | Health & Fitness |
| Shameless Care shamelesscare.com | 2 | Health & Fitness |
| Sheath sheath.com | 13 | Comedy |
| SheathUnderwear sheathunderwear.com | 3 | Comedy |
| ShipStation shipstation.com | 8 | Comedy |
| Shokz shokz.com | 2 | Education |
| Shooting Sports Life shootingsportslife.com | 1 | Leisure |
| Shopback shopback.com | 1 | Business |
| Shopify shopify.com | 79 | Society & Culture |
| Shopminnow shopminnow.com | 1 | TV & Film |
| Shopmy shopmy.us | 3 | Arts |
| Shubox theshubox.com | 1 | Education |
| Siagomininglatvia siagomininglatvia.com | 1 | Business |
| Sig Sauer sigsauer.com | 1 | Health & Fitness |
| Signupexpert signupexpert.com | 1 | Sports |
| Silentflower drinksilentflower.com | 1 | Comedy |
| Silk CIty Hot Sauce silkcityhotsauce.com | 1 | True Crime |
| SimplePractice simplepractice.com | 1 | Health & Fitness |
| SimpliSafe simplisafe.com | 6 | True Crime |
| Skims skims.com | 4 | Education |
| Skylight myskylight.com | 5 | Health & Fitness |
| Sleep sleep.me | 27 | True Crime |
| SleepCreme sleepcreme.com | 1 | True Crime |
| Slidebean slidebean.com | 1 | Technology |
| SLNT slnt.com | 1 | News |
| Slone Partners slonepartners.com | 1 | Science |
| Smalls smalls.com | 24 | News |
| Smileset smileset.com | 13 | True Crime |
| Smith smith.ai | 1 | Technology |
| Soakingwet soakingwet.com | 1 | Health & Fitness |
| SoFi sofi.com | 1 | Business |
| Sofie Pavitt Face sofiepavittface.com | 1 | Comedy |
| Sol de Janeiro soldejaneiro.com | 1 | Arts |
| Spartan spartan.com | 1 | Business |
| Speed speed.app | 1 | Technology |
| Splashsports splashsports.com | 1 | Sports |
| Spotlight spotlight-io.com | 3 | Business |
| Spring Sleep springsleep.com | 7 | News |
| Square square.com | 25 | Comedy |
| Stan stan.store | 1 | Business |
| StatsKey Pro statskey.ai | 1 | Science |
| STEK stek-usa.com | 1 | Leisure |
| Stella Blue stellabluecoffee.com | 1 | Sports |
| Stitch Fix stitchfix.com | 2 | True Crime |
| StopBox USA stopboxusa.com | 11 | News |
| Stormor stormor.com | 1 | Sports |
| Strawberry strawberry.me | 1 | News |
| Streamlabs streamlabs.com | 1 | Comedy |
| Subsplash subsplash.com | 1 | Business |
| Sundays for Dogs sundaysfordogs.com | 16 | News |
| Sunlighten sunlighten.com | 4 | Health & Fitness |
| SUNSET LAKE CBD sunsetlakecbd.com | 1 | News |
| Superhuman superhuman.com | 6 | Technology |
| Superpower superpower.com | 33 | Comedy |
| Suppgradelabs shopsuppgradelabs.com | 1 | Health & Fitness |
| SupplyHouse supplyhouse.com | 5 | Sports |
| SurfShark surfshark.com | 16 | Sports |
| Svix svix.com | 1 | Technology |
| Swimclub swimclub.co | 1 | Health & Fitness |
| Switchsupplements switchsupplements.com | 1 | Health & Fitness |